Cardizem may also be used for purposes not listed in this medication guide. If you have recently had a head injury or a heart attack. AHFS Patient Medication Information. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. To help you remember, take it at the same times each day. Mehta D. Herbal & dietary supplements. Along with its needed effects, a medicine may cause some unwanted effects. Instead, the best way to dispose of your medication is through a medicine take-back program. http://www.upandaway.org. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. For details see our conditions. https://naturalmedicines.therapeuticresearch.com. Mayo Clinic; 2021. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. Ask your pharmacist any questions you have about refilling your prescription. Consult your doctor before breast-feeding. Duplication for commercial use must be authorized by ASHP. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. Almost 70% of older adults use them. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Many herbal supplements can interact with prescription drugs. The site is secure. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. What special precautions should I follow? Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Take them to your local pharmacy which will dispose of them for you. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. 2023 Lybrate, Inc. All rights reserved. A randomized, double-blind, cross-over study. Journals of the American College of Cardiology. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Are you looking for information on isosorbide dinitrate (Isordil) instead? Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Isosorbide mononitrate systemic 60 mg (A ID). Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Sept. 26, 2022. other information we have about you. Isosorbide mononitrate (Monoket) can cause some serious health issues. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). https://naturalmedicines.therapeuticresearch.com. Does isosorbide mononitrate (Monoket) affect your kidneys? A very serious allergic reaction to this drug is rare. To use the sharing features on this page, please enable JavaScript. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Alcohol or marijuana (cannabis) can make you more dizzy. Bookshelf If concomitant therapy cannot be avoided, monitor clinical effects of the . If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. No, that's not true all the time. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Clin Res Cardiol. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Alcohol can make the side effects from isosorbide worse. If we combine this information with your protected It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. The extended-release tablet usually is taken once daily in the morning. For haemoglobin formation vit. . 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. Aspirin has an average rating of Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma If this worries you, talk to your doctor or pharmacist about other options. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Portions of this document last updated: Feb. 01, 2023. My cardiologist recommended I get on metropolol. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Drug information provided by: IBM Micromedex. 8.0 out of 10 from a total of All rights reserved. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To view a report comparing 3 (or more) medications, please sign in or create an account. Isosorbide mononitrate belongs to the group of medicines called nitrates. Am J Ther. But only about 25% of people who take herbal supplements tell their health care providers. What are the side effects of Isosorbide Mononitrate ? Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Do not keep out-of-date or unwanted medicines. Isosorbide may cause other side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. government site. View more. Liperoti R, et al. In: Current Medical Diagnosis & Treatment 2022. If you notice other effects not listed above, contact your doctor or pharmacist. Do not store in the bathroom. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. eCollection 2021. It is best not to drink alcohol while you are on isosorbide mononitrate. What side effects can this medication cause? Yet many herbal supplements may interact with heart disease medicines. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Even if the medication is working, you may experience some unwanted side effects. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. This should pass after a few days. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. Some don't work well with prescription medicines. These side effects may go away during treatment as your body adjusts to the medicine. The tablet usually is taken two or three times daily. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Do not change the dosing times unless directed by your doctor. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Generic alternatives may be available. Store it at room temperature and away from excess heat and moisture (not in the bathroom). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. 2010; doi:10.1016/j.jacc.2009.07.074. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Take the missed dose as soon as you remember it. The effects of this exposure on a nursing infant are unknown. Make sure laboratory personnel and all your doctors know you use this drug. Consult your pharmacist or local waste disposal company. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Browse all drugs on eHealthMe. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. In: Textbook of Natural Medicine. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Isosorbide mononitrate has an average rating of Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Accessed Sept. 7, 2022. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Isosorbide controls chest pain but does not cure coronary artery disease. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. A single copy of these materials may be reprinted for noncommercial personal use only. Click here for an email preview. The extended-release capsule usually is taken once daily. Higher dosages are associated with stomach irritation and This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Take your next dose at the regular time. Dated October 2016. 7.6 out of 10 from a total of Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. What special dietary instructions should I follow? Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Talk to your provider if you notice your chest pain starts to get worse. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. This content does not have an Arabic version. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Store at room temperature away from light and moisture. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. St. John's wort. Careers. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). This content does not have an English version. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. Generic alternatives may be available. WebMD does not provide medical advice, diagnosis or treatment. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. https://naturalmedicines.therapeuticresearch.com. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Do not stop taking it without consulting your doctor. We comply with the HONcode standard for trustworthy health information. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Call your doctor if you have any unusual problems while you are taking this medication. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). 67% of reviewers reported a positive effect, while 13% reported a negative effect. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. We study 23,548 Isosorbide mononitrate users. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Copyright 2023 IBM Watson Health. https://naturalmedicines.therapeuticresearch.com. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Accessed Sept. 7, 2022. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Zhonghua Yi Xue Za Zhi (Taipei). Advertising revenue supports our not-for-profit mission. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. It works and leaves the body quickly, so it needs to be taken twice a day. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . These headaches may be a sign that the medication is working as it should. Botanical medicine A modern perspective. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. Hawthorn. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Read our editorial policy. An official website of the United States government. During pregnancy, this medication should be used only when clearly needed. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. I would rather take the chance of a heart attack than have no quality of life. Isosorbide mononitrate: isosorbide mononitrate. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Is it safe to drive while on this medicine? Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Selected from data included with permission and copyrighted by First Databank, Inc. Discuss the risks and benefits with your doctor. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Isosorbide mononitrate works in two ways. This medicine is for you. 55 ratings on Drugs.com. Normal ecg doesn't rule out heart disease. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. [2] You may report side effects to Health Canada at 1-866-234-2345. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Isosorbide mononitrate helps to prevent angina chest pain from developing. May also be prescribed off label for Esophageal Spasm. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Is not subject to the Controlled Substances Act. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Side effects : headache, mild dizziness Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen.
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